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MRCP Part 1 · content check draft

Electrolyte & Osmolality Decisions Lab

Recognise the pattern, calculate the trajectory and act before the result becomes an arrest.

Not in the learner journeyClinical sign-off pending · source checked

Fictional educational cases. Independent Clinora teaching, not an official MRCP examination or substitute for local emergency pathways.

0/12 attempted · 0 correct

Sodium emergency

Seizure in profound hyponatraemia

EL-01

A 63-year-old taking a thiazide has a generalised seizure and reduced consciousness. Sodium is 112 mmol/L; glucose is normal. Duration is uncertain.

Na⁺112 mmol/LK⁺3.1 mmol/LSerum osm238 mOsm/kgGlucose5.6 mmol/L

24-hour trajectory simulator

Serum sodium

0 h24 h112117.0 mmol/L
Teaching safe-zone5.0 mmol/L change over 24 hours
Educational visualisation only. Real targets depend on the disorder, chronicity, symptoms, treatment phase and local protocol.

Reveal the calculation

What is the immediate treatment?