Endocrinology and acute medicine · FICTIONAL CASE

The glucose is falling—but the ketoacidosis is not resolved

Track ketone clearance and acidosis rather than glucose alone, preserve insulin-driven resolution and anticipate potassium risk.

Biochemical targets and treatment continuity15 minutes0/3 decisions explored
PAUSE BEFORE USING

This is educational content, not a clinical protocol. Verify current guidance, use local pathways and seek appropriate senior or specialist help.

THE CASE

A fictional 32-year-old with type 1 diabetes is receiving protocol treatment for DKA. Glucose has fallen substantially, but ketones remain elevated and bicarbonate remains low.

01 · INITIAL PRESENTATION

Listen for the assumption.

SHO

The glucose is near target, so I was preparing to stop the fixed-rate insulin infusion.

Registrar

Which biochemical process are we actually trying to stop?

SHO

Ketogenesis. We need to continue protocol-directed insulin, add glucose when indicated and monitor ketones, acidosis and potassium until resolution criteria are met.

WHERE IS THE CONSULTANT?

Choose an answer below and reveal the reasoning to see consultant feedback at every checkpoint. The full consultant-led synthesis follows after all three decisions.

Go to the first decision ↓
EVOLVING INFORMATION

The picture develops.

  1. Blood ketones remain elevated
  2. Venous bicarbonate remains low
  3. Potassium is falling during treatment
02 · DECISION CHECKPOINTS

Commit before you reveal.

After you select an option, reveal the model reasoning and the consultant’s feedback.

DECISION 1What best indicates therapeutic progress?
DECISION 2Why may glucose infusion be added while insulin continues?
DECISION 3Which electrolyte needs especially close surveillance?
03 · CONSULTANT-LED SYNTHESIS

Hear the senior team refine the plan.

The registrar tests the plan, the consultant synthesises the key principle, and the SHO confirms the safer next steps.

Registrar

I want hourly metabolic targets, fluid balance and a trigger for senior review if improvement is inadequate.

Consultant

Also identify the precipitant, confirm basal insulin continuity where appropriate and plan the transition from intravenous insulin safely.

SHO

I will hand over ketone, bicarbonate, glucose and potassium trends—not simply that the glucose has improved.

CLINORA DECISION TRACE
01 · CUEFalling glucose with persistent ketonaemia and acidosis
02 · INTERPRETDKA remains active despite glycaemic improvement
03 · ACTContinue protocol insulin, support with glucose when indicated and monitor resolution targets
SAFETY CHECK

What must remain explicit.

  • Use the current JBDS and local adult DKA protocol.
  • Monitor potassium, glucose, ketones, acid-base status and fluid balance at protocol intervals.
  • Escalate inadequate biochemical improvement, hypokalaemia, hypoglycaemia or neurological deterioration.
COMMON ERRORS

Where reasoning fails.

  • Stopping insulin when glucose normalises
  • Failing to track ketones and bicarbonate
  • Overlooking the precipitating illness
STRUCTURED HANDOVER
DKA treatment started [time]; glucose [trend], ketones [trend], bicarbonate/pH [trend], potassium [trend/replacement], fluids [balance] and precipitant [status]. Resolution criteria are [met/not met].
REFLECTIVE PAUSE

Which four trends would you insist on seeing before accepting a DKA handover?