FRCS (ORL-HNS) · SECTION 1 SBA

Adenoid cystic carcinoma and perineural spread

A patient has adenoid cystic carcinoma of the submandibular gland with numbness in the lower lip. MRI shows enhancement tracking along a named nerve toward the skull base. What is the critical treatment-planning implication?

CHOOSE ONE ANSWER

Best of five

  1. A. Map the full neural pathway in the surgical and radiotherapy plan
  2. B. Use a narrow excision around the gland only
  3. C. Assume numbness is unrelated to the tumour
  4. D. Offer neck dissection as the only treatment
  5. E. Stop follow-up at five years
ANSWER AND REASONING

A. Map the full neural pathway in the surgical and radiotherapy plan

Perineural spread can extend beyond the visible mass. Local control requires multidisciplinary planning that accounts for proximal nerve extent and the functional consequences of treatment.

Why every option is right or wrong

A. Map the full neural pathway in the surgical and radiotherapy plan: Perineural spread can extend beyond the visible mass. Local control requires multidisciplinary planning that accounts for proximal nerve extent and the functional consequences of treatment.

B. Use a narrow excision around the gland only: This risks leaving subclinical neural disease.

C. Assume numbness is unrelated to the tumour: New sensory deficit is a red flag for neural involvement.

D. Offer neck dissection as the only treatment: Regional management does not replace local neural-pathway control.

E. Stop follow-up at five years: Late recurrence is recognised in adenoid cystic carcinoma.

What if the scenario changed?

If imaging excluded neural spread and margins were clear, local treatment volumes and morbidity discussions might differ.